Allyl methyl sulfide

Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications[1][2][3].

Product Specifications

CAS Number

[10152-76-8]

UNSPSC

12352100

Hazard Statement

H225

Target

Endogenous Metabolite; GLUT; NF-κB; SOD

Type

Natural Products

Related Pathways

Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/allyl-methyl-sulfide.html

Purity

98.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

C=CCSC

Molecular Formula

C4H8S

Molecular Weight

88.17

Precautions

H225

References & Citations

[1]Sujithra K, et al. Allyl methyl sulfide, an organosulfur compound alleviates hyperglycemia mediated hepatic oxidativestress and inflammation in streptozotocin - induced experimental rats. Biomed Pharmacother. 2018 Nov;107:292-302.|[2]Sujithra K, et al. Allyl methyl sulfide, a garlic active component mitigates hyperglycemia by restoration of circulatory antioxidant status and attenuating glycoprotein components in streptozotocin-induced experimental rats. Toxicol Mech Methods. 2019 Mar;29 (3) :165-176. |[3]Qin W, et al. Quantification of Allyl Methyl Sulfide, Allyl Methyl Sulfoxide, and Allyl Methyl Sulfone in Human Milk and Urine After Ingestion of Cooked and Roasted Garlic. Front Nutr. 2020 Sep 18;7:565496.