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CD10 (CB-CALLA), CF514 conjugate, 0.1mg/mL

CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA) ) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

CD10; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen (CALLA) ; Enkephalinase; gp100; Membrane metalloendopeptidase; Neutral endopeptidase

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

MME

Gene ID

4311

NCBI Gene ID

307734

UniProt

P08473

Swiss Prot

P08473

Host

Mouse

Species Reactivity

Human

Reactivity

CD10

Immunogen

Human CD10

Target Antigen

CD10

Clonality

Monoclonal

Clone

CB-CALLA

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow (verified) |Flow, surface (published) |IF (verified)

Field of Research

Immunology, Proteases

Positive Control

Tonsil, small intestine, kidney

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

100 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Immunology (2011) 134: 419-433. (Flow, surface) Blood (2015) 125(20): 3144-3152. (Flow, surface)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF514

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