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Isosteviol (Standard)

Isosteviol (Standard) is the analytical standard of Isosteviol. This product is intended for research and analytical applications. Isosteviol ((-) -Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects[1][2][3][4].

Product Specifications

CAS Number

27975-19-5

Product Name Alternative

(-) -Isosteviol (Standard) ; iso-Steviol (Standard)

UNSPSC

12352211

Target

Interleukin Related; Reactive Oxygen Species (ROS) ; Reference Standards; Topoisomerase

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/isosteviol-standard.html

Smiles

C[C@]([C@]1([H])CC2)(CCC[C@@]1(C)C(O)=O)[C@@]3([H])[C@@]2(CC4=O)C[C@]4(C)CC3

Molecular Formula

C20H30O3

Molecular Weight

318.45

References & Citations

[1]Wong KL, et al. Isosteviol acts on potassium channels to relax isolated aortic strips of Wistar rat. Life Sci. 2004 Mar 26;74 (19) :2379-87.|[2]Wong KL, et al. Isosteviol as a potassium channel opener to lower intracellular calcium concentrations in cultured aortic smooth muscle cells. Planta Med. 2004 Feb;70 (2) :108-12.|[3]Wong KL, et al. Antiproliferative effect of isosteviol on angiotensin-II-treated rat aortic smooth muscle cells. Pharmacology. 2006;76 (4) :163-9.|[4]Asad Ullah, et al. Bioactivity Profile of the Diterpene Isosteviol and its Derivatives. Molecules. 2019 Feb 14;24 (4) :678.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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