Carmustine
Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.
Product Specifications
CAS Number
[154-93-8]
Product Name Alternative
BCNU
UNSPSC
12352211
Hazard Statement
H300, H350, H360
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Carmustine.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(NCCCl)N(CCCl)N=O
Molecular Formula
C5H9Cl2N3O2
Molecular Weight
214.05
Precautions
H300, H350, H360
References & Citations
[1]Hung CF. Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells. Neurochem Res. 2000 Jun;25 (6) :845-51.|[2]Demir A, et al. The effect of trimetazidine on intrahepatic cholestasis caused by carmustine in rats. Hepatol Res. 2001 May 1;20 (1) :133-143.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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