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Human Tau-441 K18 (P301L) Pre-formed Fibrils Protein, Tag Free

Selected Variant

TAU-H5113-100ug

Size: 100 µg

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Product Specifications

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Specifications

This protein carries no "tag". The protein has a calculated MW of 13.8 kDa.

Accession Number

P10636-8 (P301L)

Expression Region

Gln 244 - Glu 372

Host

E. coli

Target

Tau

Conjugation

Unconjugated

Tag

Native

Source

Human

Applications

1. Sonication Conditions, Dissolution, Aliquoting, Storage, and Notes for PFFThawing:Aliquoting:Storage:Sonication:Note:2. Recommendations for PFF Use in Animal ModelsMinimize Freeze-Thaw Cycles:PFF Maintenance During Injections:

Stability

The product should be stored at -70°C or room temperature for short storage. Do not store fibrils on ice or at 4°C; The unsonicated fibril is validated to be stable after storage at -70°C for 1 year under sterile conditions; The sonicated fibril should be stored at -70°C for not more than 8 weeks.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Liquid

Buffer

PBS, pH7.4

Molecular Weight

13.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

100ug*1

Host or Source

E. coli

Species

Human

Protein ID

P10636-8 (P301L)

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