AI-10-104
AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1].
Product Specifications
CAS Number
[1881276-00-1]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
RUNX
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ai-10-104.html
Purity
98.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC(F)(F)OC1=CC=C2N=C(C3=NC=CC=C3OC)NC2=C1
Molecular Formula
C14H10F3N3O2
Molecular Weight
309.24
Precautions
H315, H319, H335
References & Citations
[1]Zhou N, et al., RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019 Aug;33 (8) :2006-2021.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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