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AI-10-104

AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1].

Product Specifications

CAS Number

1881276-00-1

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

RUNX

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ai-10-104.html

Purity

98.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

FC(F)(F)OC1=CC=C2N=C(C3=NC=CC=C3OC)NC2=C1

Molecular Formula

C14H10F3N3O2

Molecular Weight

309.24

Precautions

H315, H319, H335

References & Citations

[1]Zhou N, et al., RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019 Aug;33 (8) :2006-2021.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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