Flurochloridone
Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. Flurochloridone induces endoplasmic reticulum (ER) stress and activated unfolded protein response (UPR) signaling pathways. Flurochloridone impairs cell viability and induces cytotoxicity and apoptosis mediated by ER stress via activating eIF2α-ATF4/ATF6-CHOP-Bim/Bax signaling pathways in TM4 cells[1][2].
Product Specifications
CAS Number
[61213-25-0]
Product Name Alternative
R-40244
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/flurochloridone.html
Purity
99.61
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C1N(CC(C1Cl)CCl)C2=CC=CC(C(F)(F)F)=C2
Molecular Formula
C12H10Cl2F3NO
Molecular Weight
312.12
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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