PCBP2 Rabbit mAb [KD Validated] Antibody
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly (rC) -binding protein. Binds also poly (rU) . Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
Product Specifications
Product Name Alternative
Alpha CP2; Cbp; CTBP; hnRNP E2; Hnrnpx; HNRPE2; Hnrpx; PCBP2
UniProt
Q15366
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human PCBP2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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