PROTAC CBP/P300 Degrader-1
PROTAC CBP/P300 Degrader-1 is a potent PROTAC CBP/P300 degrader. PROTAC CBP/P300 Degrader-1 potently inhibited cell viability of multiple cancer cell lines[1].
Product Specifications
CAS Number
[2484739-48-0]
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-cbp-p300-degrader-1.html
Purity
99.91
Solubility
DMSO : 173.33 mg/mL (ultrasonic)
Smiles
O=C(N1CC2=C(CC1)N(C(CC3)CCN3C(CCCCCNC4=C(C(N5C(CCC6=O)C(N6)=O)=O)C(C5=O)=CC=C4)=O)N=C2N7C8=CC(C(F)F)=C(C(C=N9)=CN9C)C=C8CCC7)NC
Molecular Formula
C46H53F2N11O6
Molecular Weight
893.98
References & Citations
[1]Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. WO2020173440A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
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