TAT-CIRP
Product Specifications
UNSPSC Description
TAT-CIRP is a a small peptide, refers to Trans-trans-activating (Tat)-cold-inducible RNA binding protein. TAT-CIRP is an inhibitor of myeloid differentiation protein 2 (MD2). TAT-CIRP exhibits robust neuroprotection against ischemic and hemorrhagic stroke in mice[1].
Target Antigen
Toll-like Receptor (TLR)
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tat-cirp.html
Purity
98.32
Solubility
10 mM in DMSO
Smiles
O=C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(NCC(NCC(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC2=CC=C(C=C2)O)C(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N
Molecular Weight
2997.31
References & Citations
[1]Fang Z, et al. An MD2-perturbing peptide has therapeutic effects in rodent and rhesus monkey models of stroke. Sci Transl Med. 2021 Jun 9;13(597):eabb6716.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5117/TAT-CIRP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5117/TAT-CIRP-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Curated Selection
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