(4-NH2) -Exatecan-d5
(4-NH2) -Exatecan-d5 is a deuterated labeled (4-NH2) -Exatecan[1]. (4-NH2) -Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2) -Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) [2].
Product Specifications
Product Name Alternative
AZ14170132-d5
UNSPSC
12352005
Hazard Statement
H301
Target
ADC Payload; Isotope-Labeled Compounds; Topoisomerase
Type
Isotope-Labeled Compounds
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.62
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5N)=CC6=C1COC([C@]6(O)C([2H])([2H])C([2H])([2H])[2H])=O
Molecular Formula
C23H16D5N3O4
Molecular Weight
408.46
Precautions
H301
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145397S/4-NH2-Exatecan-d5-SDS-MedChemExpress.pdf
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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