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CLK1-IN-1

CLK1-IN-1 is a potent and selective of Cdc2-like kinase 1 (CLK1) inhibitor, with an IC50 of 2 nM.

Product Specifications

CAS Number

2123491-32-5

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/CLK1-IN-1.html

Purity

98.55

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[C@@H](C1=CC=C(F)C=C1)N2N=NC3=C2C4=CC(C5=CC=C6C(N=CO6)=C5)=CC=C4N=C3

Molecular Formula

C24H16FN5O

Molecular Weight

409.42

Precautions

H302, H315, H319

References & Citations

[1]Sun QZ, et al. Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers. J Med Chem. 2017 Jul 27;60 (14) :6337-6352.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CLK

Available Sizes

Frequently Asked Questions

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