Antiproliferative agent-63

Antiproliferative agent-63 (compound 4d), a ring-annulated analogue of Cannabidiol, is an anticancer agent. Antiproliferative agent-63 demonstrates a promising activity against breast and colorectal cancer. Antiproliferative agent-63 arrests the G1 phase of the cell cycle and induces apoptosis via the mitochondrial pathway in breast cancer cell lines[1].

Product Specifications

CAS Number

[3048082-38-5]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-63.html

Smiles

OC1=C(C2=C(C(CCCCC)=C1)CN(CO2)CCCC)[C@@]3(C=C(CC[C@@]3([H])C(C)=C)C)[H]

Molecular Formula

C27H41NO2

Molecular Weight

411.62

References & Citations

[1]Pankaj Singh Cham, et al. Discovery of Ring-Annulated Analogues of Cannabidiol as Potential Anticancer Agents: Synthesis and Biological Evaluation. ACS Med. Chem. Lett. October 17, 2024.