Amino-PEG3-C2-acid
Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG3-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[784105-33-5]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg3-c2-acid.html
Purity
99.94
Solubility
DMF : 3.33 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CCOCCOCCOCCN
Molecular Formula
C9H19NO5
Molecular Weight
221.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. WO2019173911A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
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