SBI-993

SBI-993 is a SBI-477 analog with improved potency and suitable pharmacokinetic properties for in vivo bioavailability. SBI-993 stimulates insulin signaling by deactivating the transcription factor MondoA[1].

Product Specifications

CAS Number

[2073059-82-0]

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sbi-993.html

Concentration

10mM

Purity

98.67

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=NC(C2=CC=C(OC)C=C2)=CS1)C3=CC=C(NCC(N4CCOCC4)=O)C=C3

Molecular Formula

C23H24N4O4S

Molecular Weight

452.53

References & Citations

[1]Byungyong Ahn, et al. MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. J Clin Invest. 2016 Sep 1;126 (9) :3567-79.