Nicosulfuron-d6

Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].

Product Specifications

CAS Number

[1189419-41-7]

UNSPSC

12352005

Target

Acetolactate Synthase (ALS)

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Purity

98.4

Solubility

10 mM in DMSO

Smiles

CN(C)C(C1=C(N=CC=C1)S(NC(NC2=NC(OC([2H])([2H])[2H])=CC(OC([2H])([2H])[2H])=N2)=O)(=O)=O)=O

Molecular Formula

C15H12D6N6O6S

Molecular Weight

416.44

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Louis Carles, et al. Nicosulfuron Degradation by an Ascomycete Fungus Isolated From Submerged Alnus Leaf Litter. Front Microbiol. 2018 Dec 19;9:3167.