Recombinant Mouse Cardiotrophin-1 protein (Ctf1) (Active)
Product Specifications
Background
Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST, gp130 receptor.
Product Name Alternative
CT-1
Gene ID
13019
UniProt
Q60753
Target
MSQREGSLED HQTDSSISFL PHLEAKIRQT HNLARLLTKY AEQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSVLPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP GPEPVTVATL FTANSTAGIF SAKVLGFHVC GLYGEWVSRT EGDLGQLVPG GVA
Purification
>95% as determined by SDS?PAGE and HPLC.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF?1 cells is less than 0.5 ng, ml, corresponding to a specific activity of 2.0 106 IU, mg.
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Calculated Molecular Weight
21.5 kDa
Formulation
0.2 ?m filtered 20 mM PB, pH 7.4, 150mM NaCl , lyophilized
Host or Source
E.Coli
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