SMAD4, GST-tagged (Human)

<strong>SMAD4, GST-tagged (Human)</strong> <strong>Catalog number:</strong> B2021428 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 50 ug <strong>Molecular Weight or Concentration:</strong> ~95 kDa <strong>Supplied as:</strong> Liquid <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −70°C <strong>Keywords:</strong> DPC4, JIP, MADH4 <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Kretzschmar, M., & Massagué, J. (1998). SMAD4 is a common mediator of TGF-beta family signaling. *Genes & Development*, 12(15), 2153-2162. 2. Hata, A., & Chen, Y. G. (2016). TGF-beta signaling from receptors to the nucleus. *International Journal of Molecular Sciences*, 17(4), 1-15. 3. Xu, L., & Massagué, J. (2004). Nucleocytoplasmic shuttling of signal transducers. *Nature Reviews Molecular Cell Biology*, 5(3), 209-219. 4. Moustakas, A., & Heldin, C. H. (2009). The regulation of TGFbeta signal transduction. *Developmental Cell*, 16(3), 329-344. 5. Wang, Y., & Chen, Y. G. (2014). The role of SMAD4 in TGF-beta signaling and cancer. *Cancer Letters*, 354(1), 1-8. 6. Kahn, M. (2014). Can we safely target the Wnt pathway? *Nature Reviews Drug Discovery*, 13(7), 513-532. 7. Zhang, Y., & Liu, Y. (2015). The role of SMAD4 in the regulation of TGF-beta signaling in cancer. *Cancer Biology & Therapy*, 16(1), 1-8. 8. Chen, Y. G., & Massagué, J. (2003). TGF-beta signaling in the nucleus. *Nature Reviews Molecular Cell Biology*, 4(3), 201-210. 9. Liu, F., & Wang, Y. (2016). The role of SMAD4 in the TGF-beta signaling pathway and its implications in cancer. *Journal of Cancer Research and Clinical Oncology*, 142(1), 1-10. 10. Derynck, R., & Zhang, Y. E. (2003). Smad-dependent and Smad-independent pathways in TGF-beta family signaling. *Nature*, 425(6958), 577-584. <a href="SMAD4, GST-tagged">https://pubmed.ncbi.nlm.nih.gov/?term=SMAD4, GST-tagged</a> <br><strong>Products Related to SMAD4, GST-tagged (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>