NCS-MP-NODA
NCS-MP-NODA (NODA-Bz-SCN) is a bifunctional chelator that can be used to bind to the labeled peptide DK222 with high specificity for PD-L1. The corresponding fluorinated radioactive is synthesized by the aluminum fluoride method, and NCS-MP-NODA targets DK222 to obtain the radioactive analog [18/19F]DK222. [18F]DK222 can quantify PD-L1 in vivo via PET tracking in xenograft models of multiple cancer types.
Product Specifications
CAS Number
[1374994-81-6]
Product Name Alternative
NODA-Bz-SCN
UNSPSC
12352203
Target
Radionuclide-Drug Conjugates (RDCs)
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ncs-mp-noda.html
Smiles
O=C(CN1CCN(CCN(CC1)CC2=CC=C(C=C2)N=C=S)CC(O)=O)O
Molecular Formula
C18H24N4O4S
Molecular Weight
392.47
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
RDC Bifunctional Chelator
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Breast cancer tissue array (screening of Her-2 positive samples), including pathology grade, TNM, clinical stage and IHC markers (Her-2) results, 72 cases/72 cores
