Herpotrichone A

Herpotrichone A shows potent anti-neuroinflammatory activity in lipopolysaccharide (LPS) -induced BV-2 microglial cells with the half maximal inhibitory concentration (IC50) value of 0.41 μM.

Product Specifications

CAS Number

[2411834-17-6]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/herpotrichone-a.html

Solubility

10 mM in DMSO

Smiles

CCC[C@@H]1[C@@]23C([C@H](O[C@H]([C@]3([H])CC4=C1C(OC)=CC(O4)=O)C)OC)=C[C@]5([H])[C@](O5)([H])C2=O

Molecular Formula

C22H26O7

Molecular Weight

402.44

References & Citations

[1]Han WB, et al. Herpotrichones A and B, Two Intermolecular [4 + 2] Adducts with Anti-Neuroinflammatory Activity from a Herpotrichia Species. Org Lett. 2020 Jan 17;22 (2) :405-409.