Ibuprofenamine (free base)

Ibuprofenamine free base (Ibuprofen diethylaminoethyl ester), the prodrug of Ibuprofen (HY-78131), is a transdermal nonsteroidal anti-inflammatory agent (NSAID) . Ibuprofenamine free base can be used for the study of rheumatoid arthritis and osteoarthritis[1].

Product Specifications

CAS Number

[64622-41-9]

Product Name Alternative

Ibuprofen diethylaminoethyl ester

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ibuprofen-diethylaminoethyl-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(C(C1=CC=C(C=C1)CC(C)C)C)OCCN(CC)CC

Molecular Formula

C19H31NO2

Molecular Weight

305.45

References & Citations

[1]Xie P, et al. Safety, Tolerability, and Pharmacokinetics of Ibuprofenamine Hydrochloride Spray (NSAIDs), a New Drug for Rheumatoid Arthritis and Osteoarthritis, in Healthy Chinese Subjects. Drug Des Devel Ther. 2021 Feb 16;15:629-638.