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1-Oleoyl lysophosphatidic acid (sodium) (GMP)

Selected Variant

HY-107614G

Size: 1 Each

1-Oleoyl lysophosphatidic acid sodium (GMP) is a GMP-grade 1-Oleoyl lysophosphatidic acid sodium that can be used as an auxiliary reagent in cell therapy. 1-Oleoyl lysophosphatidic acid sodium can stimulate neuronal differentiation in neural progenitor cells from mice or rats, and it also promotes the differentiation of human adipose-derived mesenchymal stem cells into myofibroblast-like cells in vitro by activating the autocrine TGF-β1-Smad signaling pathway[1][2].

Product Specifications

CAS Number

325465-93-8

Product Name Alternative

1-Oleoyl-sn-glycero-3-phosphate (sodium) (GMP) ; 1-Oleoyl-LPA (sodium) (GMP)

UNSPSC

12352211

Target

TGF-beta/Smad

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/1-oleoyl-lysophosphatidic-acid-sodium-gmp.html

Smiles

CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP(O)(O[Na])=O)=O

Molecular Formula

C21H40NaO7P

Molecular Weight

458.50

References & Citations

[1]Eun Su Jeon, et al. Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells. Stem Cells. 2008 Mar;26 (3) :789-97.|[2]Hui-Lin Cui, et al. Promotive action of lysophosphatidic acid on proliferation of rat embryonic neural stem cells and their differentiation to cholinergic neurons in vitro. Sheng Li Xue Bao. 2006 Dec 25;58 (6) :547-55.

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

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