LUF5771

LUF5771 is a potent allosteric recombinant luteinizing hormone (recLH) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy[1].

Product Specifications

CAS Number

[1141802-49-4]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

GnRH Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/luf5771.html

Purity

99.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1CCCC1)OC2=CC(C3=CC=CC=C3)=CC(C4=CC=CC=C4)=C2

Molecular Formula

C24H23NO2

Molecular Weight

357.44

Precautions

H315, H319

References & Citations

[1]Laura H. Heitman, et al. Substituted Terphenyl Compounds as the First Class of Low Molecular Weight Allosteric Inhibitors of the Luteinizing Hormone Receptor. Journal of Medicinal Chemistry 2009 52 (7), 2036-2042