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Dinoprost

Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL) . Dinoprost plays a key role in the onset and progression of labour[1][2].

Product Specifications

CAS Number

551-11-1

Product Name Alternative

Prostaglandin F2α; PGF2α

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; Prostaglandin Receptor

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Dinoprost.html

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O

Molecular Formula

C20H34O5

Molecular Weight

354.48

Precautions

H302, H315, H319, H335

References & Citations

[1]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47 (3) :938-45.|[2]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

FP; Human Endogenous Metabolite

Citation 01

ACS Pharmacol Transl Sci. 2025 Oct 4.|Int J Mol Sci. 2023 Apr 10;24 (8) :7012.|Nat Commun. 2023 May 9;14 (1) :2668.|Phytomedicine. 2025 May 14:143:156866.|Patent. US20250154162A1.|Patent. US20250250283A1.

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