Dinoprost

Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL) . Dinoprost plays a key role in the onset and progression of labour[1][2].

Product Specifications

CAS Number

[551-11-1]

Product Name Alternative

Prostaglandin F2α; PGF2α

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; Prostaglandin Receptor

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Dinoprost.html

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O

Molecular Formula

C20H34O5

Molecular Weight

354.48

Precautions

H302, H315, H319, H335

References & Citations

[1]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47 (3) :938-45.|[2]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.