L-Kynurenine (Standard)
Product Specifications
UNSPSC Description
L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
Target Antigen
Aryl Hydrocarbon Receptor; Endogenous Metabolite
Type
Reference Standards
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-kynurenine-standard.html
Smiles
O=C(O)[C@@H](N)CC(C1=CC=CC=C1N)=O
Molecular Weight
208.21
References & Citations
[1]Moyer BJ, et al. Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24.|[2]Sakakibara K, et al. Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels. J Pharmacol Sci. 2015 Sep;129(1):31-7.|[3]Nozaki K, et al. Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J Cereb Blood Flow Metab. 1992 May;12(3):400-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-104026R/L-Kynurenine-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-104026R/
Clinical Information
No Development Reported
CAS Number
2922-83-0
Available Sizes
Curated Selection
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