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17β-HSD5 inhibitor 3

17β-HSD5 inhibitor 3 (Compound 31) is an orally active inhibitor for 17β-HSD5 with an IC50 of 69 nM[1].

Product Specifications

CAS Number

948581-46-2

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/17β-hsd5-inhibitor-3.html

Smiles

O=C(O)C1=CN(S(=O)(C2=CC=C(Br)C=C2)=O)C3=C(Cl)C=CC=C31

Molecular Formula

C15H9BrClNO4S

Molecular Weight

414.66

References & Citations

[1]Marchais-Oberwinkler S, et al., 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol. 2011 May;125 (1-2) :66-82.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KHK-C

Frequently Asked Questions

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