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Anti-IDH1 Antibody

Mouse Monoclonal Antibody specific to IDH1

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase

Gene Name

IDH1

NCBI Gene ID

<a href="https://www.ncbi.nlm.nih.gov/gene/?term=IDH1">IDH1</a>

UniProt

O75874

Cellular Locus

Cytoplasm, cytosol, Peroxisome

Host

Mouse

Reactivity

Human

Immunogen

Synthetic peptide corresponding to the region of human IDH1 that includes a point mutation at residue 132 where Arginine (R) is changed to Histidine (H)

Target Antigen

Isocitrate dehydrogenase [NADP] cytoplasmic

Target

IDH1

Clonality

Monoclonal

Isotype

IgG1

Type

Antibody

Applications

IHC

Field of Research

Cancer research

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Tris

Additionnal Information

<br><br>Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

Human R132H-IDH1. Reactivity with other species has not been investigated.

Formulation

Tris buffer, pH 7.3-7.7, 1% BSA, 0.1% sodium azide.

Buffer pH

pH 7.3-7.7

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