[D-Ala2] Leu-Enkephalinamide

[D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases[1][2].

Product Specifications

CAS Number

[65189-64-2]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/d-ala2-leu-enkephalinamide.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](C)C(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)[C@H](CC2=CC=C(C=C2)O)N

Molecular Formula

C29H40N6O6

Molecular Weight

568.66

References & Citations

[1]V P Ranta, et al. Gradient high-performance liquid chromatographic analysis of enkephalin peptides, their metabolites, and enzyme inhibitors using combined ultraviolet and electrochemical detection II. Application to ocular permeability studies in vitro. J Chromatogr B Biomed Sci Appl. 1998 May 8;709 (1) :1-10.|[2]L S Brady, et al. Analgesic effects of intraventricular morphine and enkephalins in nondependent and morphine-dependent rats. J Pharmacol Exp Ther. 1982 Jul;222 (1) :190-7.