CLK4 Protein Active

<strong>CLK4 Protein Active</strong>_x000D_ <strong>Catalog number:</strong> B2014100_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 46 kDa_x000D_ <strong>Supplied as:</strong> N/A_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> Protein, active, 10 ¬µg_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Shen Y, Zhang H, Yao S, Su F, Wang H, Yin J, Fang Y, Tan L, Zhang K, Fan X, Zhong M, Zhou Q, He J, Zhang Z. Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy Clin Transl Med. 2022 Jan;12(1):e719._x000D_ 2: Katsu R, Onogi H, Wada K, Kawaguchi Y, Hagiwara M. Novel SR-rich-related protein clasp specifically interacts with inactivated Clk4 and induces the exon EB inclusion of Clk J Biol Chem. 2002 Nov 15;277(46):44220-8._x000D_ 3: Jain P, Karthikeyan C, Moorthy NS, Waiker DK, Jain AK, Trivedi P. Human CDC2-like kinase 1 (CLK1): a novel target for Alzheimer's disease Curr Drug Targets. 2014 May;15(5):539-50._x000D_ 4: Rosenthal AS, Tanega C, Shen M, Mott BT, Bougie JM, Nguyen DT, Misteli T, Auld DS, Maloney DJ, Thomas CJ. An inhibitor of the Cdc2-like kinase 4 (Clk4) 2010 Mar 29 [updated 2011 Mar 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010._x000D_ 5: Pan Y, Wang Y, Bryant SH. Pharmacophore and 3D-QSAR characterization of 6-arylquinazolin-4-amines as Cdc2-like kinase 4 (Clk4) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (Dyrk1A) inhibitors J Chem Inf Model. 2013 Apr 22;53(4):938-47._x000D_ 6: Schultz J, Jones T, Bork P, Sheer D, Blencke S, Steyrer S, Wellbrock U, Bevec D, Ullrich A, Wallasch C. Molecular characterization of a cDNA encoding functional human CLK4 kinase and localization to chromosome 5q35 [correction of 4q35] Genomics. 2001 Feb 1;71(3):368-70._x000D_ 7: Auld D, Shen M, Thomas C. A high-throughput screen for pre-mRNA splicing modulators 2009 May 18 [updated 2010 Sep 2]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010._x000D_ 8: Tahtouh T, Durieu E, Villiers B, Bruyre C, Nguyen TL, Fant X, Ahn KH, Khurana L, Deau E, Lindberg MF, Svre E, Miege F, Roche D, Limanton E, L'Helgoual'ch JM, Burgy G, Guiheneuf S, Herault Y, Kendall DA, Carreaux F, Bazureau JP, Meijer L. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors J Med Chem. 2022 Jan 27;65(2):1396-1417._x000D_ 9: Montes-Grajales D, Olivero-Verbel J. Computer-aided identification of novel protein targets of bisphenol A Toxicol Lett. 2013 Oct 9;222(3):312-20._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20059377">10: Tanega C, Shen M, Mott BT, Thomas CJ, MacArthur R, Inglese J, Auld DS. Comparison of bioluminescent kinase assays using substrate depletion and product formation Assay Drug Dev Technol. 2009 Dec;7(6):606-14. </a>_x000D_ _x000D_ <strong>Products Related to CLK4 Protein Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>