Kadsurenin B

Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc[1][2].

Product Specifications

CAS Number

[145701-13-9]

UNSPSC

12352005

Target

Platelet-activating Factor Receptor (PAFR)

Type

Natural Products

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/kadsurenin-b.html

Solubility

10 mM in DMSO

Smiles

CO[C@@]([C@@H]1O)(C=C2CC=C)[C@@H]([C@@H](C3=CC=C4C(OCO4)=C3)[C@]1([H])C2=O)C

Molecular Formula

C20H22O5

Molecular Weight

342.39

References & Citations

[1]Ma Y, et al. Studies on PAF antagonistic bicyclo (3,2,1) octanoid neolignans from Piper kadsura. Yao Xue Xue Bao. 1993;28 (3) :207-11. |[2]Fan D, et al. Lignans from the genus Piper L. and their pharmacological activities: An updated review. Fitoterapia. 2023 Mar;165:105403.