SSTR5 antagonist 2 (hydrochloride)

SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM) [1].

Product Specifications

CAS Number

[2988224-31-1]

Product Name Alternative

4-Hydroxy-TEMPO-d17,15N,4-Hydroxy-TEMPO,4-Hydroxy-TEMPO-d25

UNSPSC

12352005

Target

Somatostatin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sstr5-antagonist-2-hydrochloride.html

Purity

98.85

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

FC(C=C1)=CC=C1C2=C(OCC)C=C(CN3CCC4(CN(C5=CC=C(C(O)=O)C=C5)C(C4)=O)CC3)C=C2OCC.[H]Cl

Molecular Formula

C32H36ClFN2O5

Molecular Weight

583.09

References & Citations

[1]Liu W, et al. Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition. ACS Med Chem Lett. 2018;9 (11) :1082-1087. Published 2018 Sep 12.