Acifran
Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin[1][2].
Product Specifications
CAS Number
72420-38-3
Product Name Alternative
AY 25712
UNSPSC
12352005
Target
GPR109A
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/acifran.html
Purity
99.25
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C(OC1(C)C2=CC=CC=C2)=CC1=O)O
Molecular Formula
C12H10O4
Molecular Weight
218.21
References & Citations
[1]M N Cayen, et al. The metabolic disposition of acifran, a new antihyperlipidemic agent, in rats and dogs. Xenobiotica. 1986 Mar;16 (3) :251-63. |[2]Jae-Kyu Jung, et al. Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b. J Med Chem. 2007 Apr 5;50 (7) :1445-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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