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NTR 368

NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 has helix forming propensity in the presence of micellar lipid. NTR 368 is a potent inducer of neural apoptosis[1].

Product Specifications

CAS Number

197230-90-3

UNSPSC

12352209

Target

Apoptosis

Type

Peptides

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ntr-368.html

Solubility

H2O

Smiles

[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)C)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(O)=O)=O)C)=O)CC(C)C)=O)CC(C)C)=O)C)=O)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@@H](CCC(N)=O)C(N)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N

Molecular Formula

C69H124N22O19

Molecular Weight

1565.86

References & Citations

[1]M R Hileman, et al. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 1997 Sep 29;415 (2) :145-54.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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