LMPTP inhibitor 1 (dihydrochloride)
LMPTP INHIBITOR 1 (dihydrochloride) is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A.
Product Specifications
CAS Number
[2310135-46-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/LMPTP_INHIBITOR_1_dihydrochloride.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : ≥ 64 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N(CC)CC)C1=CC=C(C2=NC3=CC=CC=C3C(NCCCN4CCCCC4)=C2)C=C1.Cl.Cl
Molecular Formula
C28H38Cl2N4O
Molecular Weight
517.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Stanford SM1, et al. Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat Chem Biol. 2017 Jun;13 (6) :624-632.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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