Dickkopf Related Protein-1 (Human)

<strong>Dickkopf Related Protein-1 (Human)</strong>_x000D_ <strong>Catalog number:</strong> B2010350_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Dickkopf Related Protein-1 (Human) expressed in HEK 293. This protein acts as a protein involved in embryonic development through its inhibition of the Wnt signaling pathway._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuDKK-1; hDkk-1; SK_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Menet R, Bourassa P, Calon F, ElAli A. Dickkopf-related protein-1 inhibition_x000D_ attenuates amyloid-beta pathology associated to Alzheimer's disease. Neurochem_x000D_ Int. 2020 Dec;141:104881._x000D_ _x000D_ 2: Auziņa D, Beinaroviča I, Janicka-Kupra B, Lejniece S, Lejnieks A, Groma V._x000D_ Dickkopf-related protein 1 expression in bone marrow of multiple myeloma_x000D_ patients: correlation with bone disease and plasma cell malignancy type. Exp_x000D_ Oncol. 2020 Dec;42(4):285-288._x000D_ _x000D_ 3: Jiang SJ, Jin ZZ, Peng YJ. Expression of Dickkopf-related Protein 1 in_x000D_ Patients with Temporomandibular Osteoarthritis after Treatment with Hyaluronic_x000D_ Acid. Curr Med Sci. 2020 Jun;40(3):574-579._x000D_ _x000D_ 4: Sui Q, Zheng J, Liu D, Peng J, Ou Q, Tang J, Li Y, Kong L, Jiang W, Xiao B,_x000D_ Chao X, Pan Z, Zhang H, Ding PR. Dickkopf-related protein 1, a new biomarker for_x000D_ local immune status and poor prognosis among patients with colorectal liver_x000D_ Oligometastases: a retrospective study. BMC Cancer. 2019 Dec 12;19(1):1210._x000D_ _x000D_ 5: Huang X, Zhong L, van Helvoort E, Lafeber F, Mastbergen S, Hendriks J, Post_x000D_ JN, Karperien M. The Expressions of Dickkopf-Related Protein 1 and Frizzled-_x000D_ Related Protein Are Negatively Correlated to Local Inflammation and_x000D_ Osteoarthritis Severity. Cartilage. 2019 Apr 4:1947603519841676._x000D_ _x000D_ 6: Hamada-Ode K, Taniguchi Y, Shimamura Y, Fujimoto S, Terada Y. Serum dickkopf-_x000D_ related protein 1 and sclerostin may predict the progression of chronic kidney_x000D_ disease in Japanese patients. Nephrol Dial Transplant. 2019 Aug_x000D_ 1;34(8):1426-1427._x000D_ _x000D_ 7: Xiong JH, Liu J, Chen J. Clinical significance and prognostic value of tumor_x000D_ necrosis factor-α and dickkopf related protein-1 in ankylosing spondylitis._x000D_ World J Clin Cases. 2020 Apr 6;8(7):1213-1222._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31839998/">8: Zhang R, Lin HM, Broering R, Shi XD, Yu XH, Xu LB, Wu WR, Liu C. Dickkopf-1_x000D_ contributes to hepatocellular carcinoma tumorigenesis by activating the_x000D_ Wnt/β-catenin signaling pathway. Signal Transduct Target Ther. 2019 Dec 6;4:54.</a>_x000D_ _x000D_ <strong>Products Related to Dickkopf Related Protein-1 (Human) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>