PXS-4728A
Product Specifications
UNSPSC Description
PXS-4728A (BI-1467335) is a potent and orally active semicarbazide-sensitive amine oxidase (SSAO) inhibitor. PXS-4728A inhibits airway inflammation. PXS-4728A has the potential for the research of chronic obstructive pulmonary disease (COPD)[1].
Target Antigen
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pxs-4728a.html
Purity
98.79
Solubility
DMSO : 233.33 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(NC(C)(C)C)C1=CC=C(OC/C(CN)=C/F)C=C1.Cl
Molecular Weight
316.80
References & Citations
[1]A G Jarnicki, et al. The Inhibitor of Semicarbazide-Sensitive Amine Oxidase, PXS-4728A, Ameliorates Key Features of Chronic Obstructive Pulmonary Disease in a Mouse Model. Br J Pharmacol. 2016 Nov;173(22):3161-3175.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112726/PXS-4728A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112726/PXS-4728A-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1478364-68-9
Available Sizes
Curated Selection
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