HaloAUTAC tt15
HaloAUTAC tt15 is an autophagy-targeting chimera (AUTAC), that targets the Halo Tag carrying proteins, and degrades via the autophagy mechanism[1].
Product Specifications
CAS Number
[2241668-45-9]
UNSPSC
12352005
Target
AUTACs
Type
Reference compound
Related Pathways
Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/halo-protac-1.html
Purity
96.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClCCCCCCOCCOCCOCCOCCOCCNC([C@@H](NC(C)=O)CSC1=NC(C(N=C(N2)N)=O)=C2N1CC3=CC=C(C=C3)Cl)=O
Molecular Formula
C33H49Cl2N7O8S
Molecular Weight
774.76
References & Citations
[1]Takahashi D, et al., Second-Generation AUTACs for Targeted Autophagic Degradation. J Med Chem. 2023 Sep 14;66 (17) :12342-12372.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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