HJC0416 (hydrochloride)
HJC0416 hydrochloride is a potent and orally active STAT3 inhibitor with an enhanced anticancer profile than Stattic (HY-13818) . HJC0416 hydrochloride is a promising anti-cancer agent for breast cancer study[1].
Product Specifications
CAS Number
[2415263-08-8]
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hjc0416-hydrochloride.html
Purity
98.68
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C=CS2(=O)=O)C2=C1)C3=CC(Cl)=CC=C3OCCCN.[H]Cl
Molecular Formula
C18H18Cl2N2O4S
Molecular Weight
429.32
References & Citations
[1]Haijun Chen, et al.Discovery of Potent Anticancer Agent HJC0416, an Orally Bioavailable Small Molecule Inhibitor of Signal Transducer and Activator of Transcription 3 (STAT3) . Eur J Med Chem. 2014 Jul 23;82:195-203.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15335939 1 Vial
Lentiviral human CEACAM1 shRNA (UAS) - Lentiviral human CEACAM1 shRNA (UAS, GFP) (25)
Ask
View Details LS007846-20ug 20 µg
Alpha Tubulin (TUBA1A) (NM_006009) Human Over-expression Lysate
Ask
View Details 
141872 200 µL
Phospholipase A2, Lipoprotein Associated (LpPLA2, PLA2G7, PAF-AH, PAFAH, Lp-PLA2, LDL-PLA2, Platelet Activating Factor Acetylhydrolase, Plasma Phospholipase A2 Group VII)
Ask
View Details 