Boc-Pip-butyn
Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
1346153-07-8
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-pip-butyn.html
Purity
95.79
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(CC1)CCC#C)OC(C)(C)C
Molecular Formula
C14H23NO2
Molecular Weight
237.34
Precautions
H315, H319, H335
References & Citations
[1]Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61 (1) :e202110864.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Frequently Asked Questions
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