Boc-Pip-butyn

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1346153-07-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-pip-butyn.html

Purity

95.79

Solubility

10 mM in DMSO

Smiles

O=C(N1CCC(CC1)CCC#C)OC(C)(C)C

Molecular Formula

C14H23NO2

Molecular Weight

237.34

Precautions

H315, H319, H335

References & Citations

[1]Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61 (1) :e202110864.