Pifithrin-α (hydrobromide)
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.
Product Specifications
CAS Number
63208-82-2
Product Name Alternative
Pifithrin hydrobromide; PFTα hydrobromide
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Aryl Hydrocarbon Receptor; Ferroptosis; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Pifithrin-_alpha_-hydrobromide.html
Purity
98.58
Solubility
DMSO : ≥ 50 mg/mL|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N=C1SC2=C(CCCC2)N1CC(C3=CC=C(C)C=C3)=O.[H]Br
Molecular Formula
C16H19BrN2OS
Molecular Weight
367.30
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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