(E) -Akt inhibitor-IV
(E) -Akt inhibitor-IV ((E) -AKTIV) is a PI3K-Akt inhibitor, with potent cytotoxic[1].
Product Specifications
CAS Number
[959841-49-7]
Product Name Alternative
(E) -AKTIV
UNSPSC
12352211
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-akt-inhibitor-iv.html
Concentration
10mM
Purity
98.63
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CN(/C=C/C1=[N+](C2=CC=CC=C2)C3=CC=C(C4=NC5=CC=CC=C5S4)C=C3N1CC)C6=CC=CC=C6.[I-].[E]
Molecular Formula
C31H27IN4S
Molecular Weight
614.54
References & Citations
[1]Changkun Hu, et al. A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells. Eur J Med Chem. 2010 Feb;45 (2) :705-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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