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Heptaminol

Heptaminol is a fatty amine with pressor properties and a potential antihypotension agent. Heptaminol is also a competitive inhibitor of norepinephrine uptake and an inhibitor of nicotine-induced catecholamine release (IC50: 650 μM) . Heptaminol does not inhibit norepinephrine release induced by 59 mM K+ but rather inhibits high-affinity Na+-dependent norepinephrine uptake[1][2].

Product Specifications

CAS Number

372-66-7

UNSPSC

12352211

Hazard Statement

H302, H315, H318, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/heptaminol.html

Purity

98.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

OC(C)(CCCC(C)N)C

Molecular Formula

C8H19NO

Molecular Weight

145.25

Precautions

H302, H315, H318, H335

References & Citations

[1]Dib J, et al. Is heptaminol a (major) metabolite of octodrine? Drug Test Anal. 2019 Nov;11 (11-12) :1761-1763.|[2]Delicado EG, et al. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. Biochem Pharmacol. 1990 Aug 15;40 (4) :821-5.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

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