Naproxen Gilteritinib
Product Specifications
UNSPSC Description
Naproxen Gilteritinib is the active reference substance of Gilteritinib (HY-12432). Gilteritinib is the target protein ligand of PROTAC degrader LWY713 (HY-157213)[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/naproxen-gilteritinib.html
Smiles
O=C(C1=C(NC(C=C2OC)=CC=C2N3CCC(CC3)N4CCNCC4)N=C(C(CC)=N1)NC5CCOCC5)N
Molecular Weight
538.68
References & Citations
[1]Liu W, et al., Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. Eur J Med Chem. 2024 Jan 15;264:115974.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169374/Naproxen-Gilteritinib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169374/
Clinical Information
No Development Reported
CAS Number
1373410-40-2
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