Naproxen Gilteritinib
Naproxen Gilteritinib is the active reference substance of Gilteritinib (HY-12432) . Gilteritinib is the target protein ligand of PROTAC degrader LWY713 (HY-157213) [1].
Product Specifications
CAS Number
[1373410-40-2]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/naproxen-gilteritinib.html
Smiles
O=C(C1=C(NC(C=C2OC)=CC=C2N3CCC(CC3)N4CCNCC4)N=C(C(CC)=N1)NC5CCOCC5)N
Molecular Formula
C28H42N8O3
Molecular Weight
538.68
References & Citations
[1]Liu W, et al., Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. Eur J Med Chem. 2024 Jan 15;264:115974.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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