Asperaculane B
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC50 of 7.89 μM. Asperaculane B also inhibits the development of asexual P. falciparum with IC50 of 3 μM, and it is nontoxic to human cells[1].
Product Specifications
CAS Number
2378379-27-0
UNSPSC
12352211
Target
Endogenous Metabolite; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/asperaculane-b.html
Solubility
10 mM in DMSO
Smiles
CCC1=CC([C@]2(C)[C@@H]1CC=C(CO)C[C@@H]2O)=O
Molecular Formula
C14H20O3
Molecular Weight
236.31
References & Citations
[1]Niu G, et al. Fungal Metabolite Asperaculane B Inhibits Malaria Infection and Transmission. Molecules. 2020;25 (13) :3018. Published 2020 Jul 1.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite; Plasmodium
Frequently Asked Questions
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