Serotonin
Product Specifications
UNSPSC Description
Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
Target Antigen
5-HT Receptor; COMT; Endogenous Metabolite
Type
Natural Products
Related Pathways
GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Serotonin.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
OC1=CC2=C(NC=C2CCN)C=C1
Molecular Weight
176.22
References & Citations
[1]Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25.|[2]Shajib MS, et al. Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation. PLoS One. 2013 Aug 28;8(8):e72774.bioRxiv. 2024 November 03.|Curr Res Food Sci. 2024 Apr 26:8:100754.|Int J Mol Sci. 2022, 23(20), 12420.|J Exp Clin Cancer Res. 2024 Oct 10;43(1):284.|Authorea. September 19, 2022.|bioRxiv. 2023 Oct 13.|bioRxiv. 2024 November 03.|J Immunother Cancer. 2021 Jul;9(7):e002383.|Nature. 2024 Dec 18.|Res Sq. 2024 Jun 11.|Research Square Preprint. 2023 Dec 28.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1473A/Serotonin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1473A/Serotonin-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
50-67-9
Available Sizes
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