ECF/CCL11 Polyclonal Antibody

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

CCL; SCYA; C-C Motif Chemokine; Small-Inducible Cytokine A; CCL11; SCYA11; eotaxin; C-C Motif Chemokine 11; Eosinophil Chemotactic Protein; Eotaxin 1; Small-Inducible Cytokine A11