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Voglibose

Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis[1].

Product Specifications

CAS Number

83480-29-9

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Glycosidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Voglibose.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 250 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@@](O)(CO)C[C@H](NC(CO)CO)[C@H](O)[C@H]1O

Molecular Formula

C10H21NO7

Molecular Weight

267.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Kato J, et al. Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice. Int J Mol Sci. 2020 Mar 23;21 (6) :2226.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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