Tyrosinase-IN-12

Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors[1].

Product Specifications

CAS Number

[1860779-42-5]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS) ; Tyrosinase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tyrosinase-in-12.html

Purity

99.83

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

ClC1=CC=C(/C=N/NC2=NC(C3=CC=CC=C3)=CS2)C=C1

Molecular Formula

C16H12ClN3S

Molecular Weight

313.80

References & Citations

[1]Djafarou S, et al. Synthesis and evaluation of the antioxidant and anti-tyrosinase activities of thiazolyl hydrazone derivatives and their application in the anti-browning of fresh-cut potato. Food Chem.