ZINC000028464438
ZINC000028464438 is a selective HDAC11 inhibitor with an IC50 of 3.5 µM. ZINC000028464438 shows almost no inhibition for other HDAC subtypes[1].
Product Specifications
CAS Number
[866123-66-2]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zinc000028464438.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C(C=C1)NC(C2=CC=CC(COC3=CC=CC=C3)=N2)=O)C(NO)=O
Molecular Formula
C21H19N3O5
Molecular Weight
393.39
References & Citations
[1]Fady Baselious, et al. Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor. Int J Mol Sci. 2024 Jan 22;25 (2) :1358.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC11
Curated Selection
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