ZINC000028464438

ZINC000028464438 is a selective HDAC11 inhibitor with an IC50 of 3.5 µM. ZINC000028464438 shows almost no inhibition for other HDAC subtypes[1].

Product Specifications

CAS Number

[866123-66-2]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zinc000028464438.html

Solubility

10 mM in DMSO

Smiles

COC1=C(C=C(C=C1)NC(C2=CC=CC(COC3=CC=CC=C3)=N2)=O)C(NO)=O

Molecular Formula

C21H19N3O5

Molecular Weight

393.39

References & Citations

[1]Fady Baselious, et al. Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor. Int J Mol Sci. 2024 Jan 22;25 (2) :1358.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC11

Curated Selection

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